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New Aspects of HERG K(+) Channel Function Depending upon Cardiac Spatial Heterogeneity
HERG K(+) channel, the genetic counterpart of rapid delayed rectifier K(+) current in cardiac cells, is responsible for many cases of inherited and drug-induced long QT syndromes. HERG has unusual biophysical properties distinct from those of other K(+) channels. While the conventional pulse protoco...
Autores principales: | Zhang, Pen, Guan, Ping, Bai, Xiao-Lu, Song, Zhi-Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903466/ https://www.ncbi.nlm.nih.gov/pubmed/24475014 http://dx.doi.org/10.1371/journal.pone.0072181 |
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