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Do Optimal Prognostic Thresholds in Continuous Physiological Variables Really Exist? Analysis of Origin of Apparent Thresholds, with Systematic Review for Peak Oxygen Consumption, Ejection Fraction and BNP

BACKGROUND: Clinicians are sometimes advised to make decisions using thresholds in measured variables, derived from prognostic studies. OBJECTIVES: We studied why there are conflicting apparently-optimal prognostic thresholds, for example in exercise peak oxygen uptake (pVO(2)), ejection fraction (E...

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Detalles Bibliográficos
Autores principales: Giannoni, Alberto, Baruah, Resham, Leong, Tora, Rehman, Michaela B., Pastormerlo, Luigi Emilio, Harrell, Frank E., Coats, Andrew J. S., Francis, Darrel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903471/
https://www.ncbi.nlm.nih.gov/pubmed/24475020
http://dx.doi.org/10.1371/journal.pone.0081699