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Do Optimal Prognostic Thresholds in Continuous Physiological Variables Really Exist? Analysis of Origin of Apparent Thresholds, with Systematic Review for Peak Oxygen Consumption, Ejection Fraction and BNP
BACKGROUND: Clinicians are sometimes advised to make decisions using thresholds in measured variables, derived from prognostic studies. OBJECTIVES: We studied why there are conflicting apparently-optimal prognostic thresholds, for example in exercise peak oxygen uptake (pVO(2)), ejection fraction (E...
Autores principales: | Giannoni, Alberto, Baruah, Resham, Leong, Tora, Rehman, Michaela B., Pastormerlo, Luigi Emilio, Harrell, Frank E., Coats, Andrew J. S., Francis, Darrel P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903471/ https://www.ncbi.nlm.nih.gov/pubmed/24475020 http://dx.doi.org/10.1371/journal.pone.0081699 |
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