Proteinase Activated Receptor 1 Mediated Fibrosis in a Mouse Model of Liver Injury: A Role for Bone Marrow Derived Macrophages

Liver fibrosis results from the co-ordinated actions of myofibroblasts and macrophages, a proportion of which are of bone marrow origin. The functional effect of such bone marrow-derived cells on liver fibrosis is unclear. We examine whether changing bone marrow genotype can down-regulate the liver&...

Descripción completa

Detalles Bibliográficos
Autores principales: Kallis, Yiannis N., Scotton, Christopher J., MacKinnon, Alison C., Goldin, Robert D., Wright, Nicholas A., Iredale, John P., Chambers, Rachel C., Forbes, Stuart J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903514/
https://www.ncbi.nlm.nih.gov/pubmed/24475094
http://dx.doi.org/10.1371/journal.pone.0086241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903514/
https://www.ncbi.nlm.nih.gov/pubmed/24475094
http://dx.doi.org/10.1371/journal.pone.0086241

Ejemplares similares