Phospholipase C-β1 and β4 Contribute to Non-Genetic Cell-to-Cell Variability in Histamine-Induced Calcium Signals in HeLa Cells

A uniform extracellular stimulus triggers cell-specific patterns of Ca(2+) signals, even in genetically identical cell populations. However, the underlying mechanism that generates the cell-to-cell variability remains unknown. We monitored cytosolic inositol 1,4,5-trisphosphate (IP(3)) concentration...

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Detalles Bibliográficos
Autores principales: Ishida, Sachiko, Matsu-ura, Toru, Fukami, Kiyoko, Michikawa, Takayuki, Mikoshiba, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903530/
https://www.ncbi.nlm.nih.gov/pubmed/24475116
http://dx.doi.org/10.1371/journal.pone.0086410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903530/
https://www.ncbi.nlm.nih.gov/pubmed/24475116
http://dx.doi.org/10.1371/journal.pone.0086410

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