Functional Module Connectivity Map (FMCM): A Framework for Searching Repurposed Drug Compounds for Systems Treatment of Cancer and an Application to Colorectal Adenocarcinoma

Drug repurposing has become an increasingly attractive approach to drug development owing to the ever-growing cost of new drug discovery and frequent withdrawal of successful drugs caused by side effect issues. Here, we devised Functional Module Connectivity Map (FMCM) for the discovery of repurpose...

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Detalles Bibliográficos
Autores principales: Chung, Feng-Hsiang, Chiang, Yun-Ru, Tseng, Ai-Lun, Sung, Yung-Chuan, Lu, Jean, Huang, Min-Chang, Ma, Nianhan, Lee, Hoong-Chien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903539/
https://www.ncbi.nlm.nih.gov/pubmed/24475102
http://dx.doi.org/10.1371/journal.pone.0086299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903539/
https://www.ncbi.nlm.nih.gov/pubmed/24475102
http://dx.doi.org/10.1371/journal.pone.0086299

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