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Structural Effects of Methionine Oxidation on Isolated Subdomains of Human Fibrin D and αC Regions
Oxidation of key methionine residues on fibrin leads to altered fibrin polymerization producing severely altered fibrin gel structure and function. This is important because fibrinogen and its modification by oxidative stress have been implicated as key contributors to both pathological thrombotic a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903590/ https://www.ncbi.nlm.nih.gov/pubmed/24475207 http://dx.doi.org/10.1371/journal.pone.0086981 |