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Mycobacterium tuberculosis Subverts the TLR-2 - MyD88 Pathway to Facilitate Its Translocation into the Cytosol

Mycobacterium tuberculosis (M.tb) has evolved mechanisms to evade its destruction in phagolysosomes, where it successfully survives and replicates within phagocytes. Recent studies have shown that virulent strains of M.tb can translocate from the phagosome into the cytosol of dendritic cells (DC). T...

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Detalles Bibliográficos
Autores principales: Rahman, Md. Aejazur, Sobia, Parveen, Gupta, Neeta, Kaer, Luc Van, Das, Gobardhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903598/
https://www.ncbi.nlm.nih.gov/pubmed/24475192
http://dx.doi.org/10.1371/journal.pone.0086886