Oct4 Mediates Tumor Initiating Properties in Oral Squamous Cell Carcinomas through the Regulation of Epithelial-Mesenchymal Transition

BACKGROUND: Overexpression of Oct4, an important transcription factor of embryonic stem cells (ESC), has been reported in several cancers. The aim of this study was to determine the emerging role of Oct4 in oral squamous cell carcinoma (OSCC) both in vitro and in vivo. METHODOLOGY/PRINCIPAL FINDING:...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsai, Lo-Lin, Hu, Fang-Wei, Lee, Shiuan-Shinn, Yu, Chuan-Hang, Yu, Cheng-Chia, Chang, Yu-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903644/
https://www.ncbi.nlm.nih.gov/pubmed/24475251
http://dx.doi.org/10.1371/journal.pone.0087207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903644/
https://www.ncbi.nlm.nih.gov/pubmed/24475251
http://dx.doi.org/10.1371/journal.pone.0087207

Ejemplares similares