Cargando…

Oct4 Mediates Tumor Initiating Properties in Oral Squamous Cell Carcinomas through the Regulation of Epithelial-Mesenchymal Transition

BACKGROUND: Overexpression of Oct4, an important transcription factor of embryonic stem cells (ESC), has been reported in several cancers. The aim of this study was to determine the emerging role of Oct4 in oral squamous cell carcinoma (OSCC) both in vitro and in vivo. METHODOLOGY/PRINCIPAL FINDING:...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsai, Lo-Lin, Hu, Fang-Wei, Lee, Shiuan-Shinn, Yu, Chuan-Hang, Yu, Cheng-Chia, Chang, Yu-Chao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903644/ https://www.ncbi.nlm.nih.gov/pubmed/24475251 http://dx.doi.org/10.1371/journal.pone.0087207

Ejemplares similares

Acquisition cancer stemness, mesenchymal transdifferentiation, and chemoresistance properties by chronic exposure of oral epithelial cells to arecoline
por: Wang, Tung Yuan, et al.
Publicado: (2016)

Concurrent Expression of Oct4 and Nanog Maintains Mesenchymal Stem-Like Property of Human Dental Pulp Cells
por: Huang, Chuan-En, et al.
Publicado: (2014)

Elevated Snail Expression Mediates Tumor Progression in Areca Quid Chewing-Associated Oral Squamous Cell Carcinoma via Reactive Oxygen Species
por: Lee, Shiuan-Shinn, et al.
Publicado: (2013)

Correction: Elevated Snail Expression Mediates Tumor Progression in Areca Quid Chewing-Associated Oral Squamous Cell Carcinoma via Reactive Oxygen Species
por: Lee, Shiuan-Shinn, et al.
Publicado: (2014)

Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma
por: Krisanaprakornkit, Suttichai, et al.
Publicado: (2012)

CD133/Src Axis Mediates Tumor Initiating Property and Epithelial-Mesenchymal Transition of Head and Neck Cancer
por: Chen, Yu-Syuan, et al.
Publicado: (2011)

Oral submucous fibrosis stimulates invasion and epithelial‐mesenchymal transition in oral squamous cell carcinoma by activating MMP‐2 and IGF‐IR
por: Chen, Pei‐Ni, et al.
Publicado: (2021)

KLF7 overexpression in human oral squamous cell carcinoma promotes migration and epithelial-mesenchymal transition
por: Ding, Xiaojun, et al.
Publicado: (2017)

Epithelial-mesenchymal transition related to bone invasion in oral squamous cell carcinoma
por: Vanini, Jaqueline Vaz, et al.
Publicado: (2022)

Cudraxanthone D Regulates Epithelial-Mesenchymal Transition by Autophagy Inhibition in Oral Squamous Cell Carcinoma Cell Lines
por: Yu, Su-Bin, et al.
Publicado: (2019)

Expression of epithelial-mesenchymal transition markers at the invasive front of oral squamous cell carcinoma
por: COSTA, Liana Cristina Melo Carneiro, et al.
Publicado: (2015)

Periodontal pathogens promote epithelial-mesenchymal transition in oral squamous carcinoma cells in vitro
por: Abdulkareem, A. A., et al.
Publicado: (2017)

Immunohistochemical Expression of Epithelial Mesenchymal Transition Proteins in Squamous Cell Carcinoma of the Oral Cavity
por: Kadeh, Hamideh, et al.
Publicado: (2021)

Mesenchymal-Epithelial Transition in Oral Cancer
por: Patil, Shankargouda, et al.
Publicado: (2015)

Signaling pathways promoting epithelial mesenchymal transition in oral submucous fibrosis and oral squamous cell carcinoma
por: Shetty, Smitha Sammith, et al.
Publicado: (2020)

WISP-1 Promotes Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma Cells via the miR-153-3p/Snail Axis
por: Chang, An-Chen, et al.
Publicado: (2019)

Prognostic value of association of OCT4 with LEF1 expression in esophageal squamous cell carcinoma and their impact on epithelial‐mesenchymal transition, invasion, and migration
por: Zhao, Yue, et al.
Publicado: (2018)

Role of SIRT1 in regulation of epithelial-to-mesenchymal transition in oral squamous cell carcinoma metastasis
por: Chen, I-Chieh, et al.
Publicado: (2014)

Epithelial–mesenchymal transition in oral squamous cell carcinoma: An insight into molecular mechanisms and clinical implications
por: Jayanthi, P, et al.
Publicado: (2020)

FGF8 induces epithelial-mesenchymal transition and promotes metastasis in oral squamous cell carcinoma
por: Hao, Yilong, et al.
Publicado: (2021)

Ectopic expression of MELK in oral squamous cell carcinoma and its correlation with epithelial mesenchymal transition
por: Li, Bo, et al.
Publicado: (2021)

Butyrate promotes oral squamous cell carcinoma cells migration, invasion and epithelial-mesenchymal transition
por: Zang, Wenli, et al.
Publicado: (2022)

Hypoxia Enhances Fusion of Oral Squamous Carcinoma Cells and Epithelial Cells Partly via the Epithelial–Mesenchymal Transition of Epithelial Cells
por: Huang, Chun-ming, et al.
Publicado: (2018)

E-liquid alters oral epithelial cell function to promote epithelial to mesenchymal transition and invasiveness in preclinical oral squamous cell carcinoma
por: de Lima, Jefferson Muniz, et al.
Publicado: (2023)

Epithelial-mesenchymal transition-related gene signature for prognosis of lung squamous cell carcinoma
por: Yu, Hongmin, et al.
Publicado: (2023)

Epithelial to Mesenchymal Transition and Cell Biology of Molecular Regulation in Endometrial Carcinogenesis
por: Chiu, Hsiao-Chen, et al.
Publicado: (2019)

Eukaryotic translation initiation factor 5A-2 involves in doxorubicin-induced epithelial-mesenchymal transition in oral squamous cell carcinoma cells
por: Fang, Liang, et al.
Publicado: (2018)

FOXM1 is a novel predictor of recurrence in patients with oral squamous cell carcinoma associated with an increase in epithelial-mesenchymal transition
por: Luo, Ya-Dong, et al.
Publicado: (2019)

The Molecular Mechanism of Epithelial–Mesenchymal Transition for Breast Carcinogenesis
por: Li, Chia-Jung, et al.
Publicado: (2019)

MiR-145 Regulates Epithelial to Mesenchymal Transition of Breast Cancer Cells by Targeting Oct4
por: Hu, Jiajia, et al.
Publicado: (2012)

Epithelial-to-Mesenchymal Transition and Neoangiogenesis in Laryngeal Squamous Cell Carcinoma
por: Franz, Leonardo, et al.
Publicado: (2021)

Eribulin sensitizes oral squamous cell carcinoma cells to cetuximab via induction of mesenchymal-to-epithelial transition
por: Kitahara, Hiroko, et al.
Publicado: (2016)

MicroRNA-300 suppresses metastasis of oral squamous cell carcinoma by inhibiting epithelial-to-mesenchymal transition
por: Kang, Yuanyuan, et al.
Publicado: (2018)

DDB2 regulates Epithelial-to-Mesenchymal Transition (EMT) in Oral/Head and Neck Squamous Cell Carcinoma
por: Bommi, Prashant V., et al.
Publicado: (2018)

Carbonic Anhydrase III Promotes Cell Migration and Epithelial–Mesenchymal Transition in Oral Squamous Cell Carcinoma
por: Chu, Yin-Hung, et al.
Publicado: (2020)

LDHA Promotes Oral Squamous Cell Carcinoma Progression Through Facilitating Glycolysis and Epithelial–Mesenchymal Transition
por: Cai, Hongshi, et al.
Publicado: (2019)

Tumor-associated macrophages correlate with the clinicopathological features and poor outcomes via inducing epithelial to mesenchymal transition in oral squamous cell carcinoma
por: Hu, Yong, et al.
Publicado: (2016)

Detection of Epithelial-Mesenchymal Transition Status of Circulating Tumor Cells in Patients with Esophageal Squamous Carcinoma
por: Han, Dingpei, et al.
Publicado: (2018)

Chordin-Like 1 Regulates Epithelial-to-Mesenchymal Transition and Metastasis via the MAPK Signaling Pathway in Oral Squamous Cell Carcinoma
por: Wu, Qiuyu, et al.
Publicado: (2022)

Metronomic Cordycepin Therapy Prolongs Survival of Oral Cancer-Bearing Mice and Inhibits Epithelial-Mesenchymal Transition
por: Su, Nai-Wen, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ukp1f6b8041a3fabtpos4d3tev