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Up-Regulation of hERG K(+) Channels by B-RAF

Human ether-a-go-go related-gene K(+) channels (hERG) participate in the regulation of tumor cell proliferation and apoptosis. HERG channel activity is up-regulated by growth factors. Kinases sensitive to growth factor signaling include the serine/threonine protein kinase B-RAF. The present study th...

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Detalles Bibliográficos
Autores principales: Pakladok, Tatsiana, Hosseinzadeh, Zohreh, Almilaji, Ahmad, Lebedeva, Aleksandra, Shumilina, Ekaterina, Alesutan, Ioana, Lang, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903650/
https://www.ncbi.nlm.nih.gov/pubmed/24475291
http://dx.doi.org/10.1371/journal.pone.0087457