Cargando…

Activation of ERα Signaling Differentially Modulates IFN-γ Induced HLA-Class II Expression in Breast Cancer Cells

The coordinate regulation of HLA class II (HLA-II) is controlled by the class II transactivator, CIITA, and is crucial for the development of anti-tumor immunity. HLA-II in breast carcinoma is associated with increased IFN-γ levels, reduced expression of the estrogen receptor (ER) and reduced age at...

Descripción completa

Detalles Bibliográficos
Autores principales: Mostafa, Ahmed A., Codner, Dianne, Hirasawa, Kensuke, Komatsu, Yumiko, Young, Matthew N., Steimle, Viktor, Drover, Sheila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903652/
https://www.ncbi.nlm.nih.gov/pubmed/24475282
http://dx.doi.org/10.1371/journal.pone.0087377