Reporters Transiently Transfected into Mammalian Cells Are Highly Sensitive to Translational Repression Induced by dsRNA Expression

In mammals, double-stranded RNA (dsRNA) can mediate sequence-specific RNA interference, activate sequence-independent interferon response, or undergo RNA editing by adenosine deaminases. We showed that long hairpin dsRNA expression had negligible effects on mammalian somatic cells—expressed dsRNA wa...

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Detalles Bibliográficos
Autores principales: Nejepinska, Jana, Malik, Radek, Wagner, Susan, Svoboda, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903663/
https://www.ncbi.nlm.nih.gov/pubmed/24475301
http://dx.doi.org/10.1371/journal.pone.0087517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903663/
https://www.ncbi.nlm.nih.gov/pubmed/24475301
http://dx.doi.org/10.1371/journal.pone.0087517

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