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The Actin-Binding Proteins Eps8 and Gelsolin Have Complementary Roles in Regulating the Growth and Stability of Mechanosensory Hair Bundles of Mammalian Cochlear Outer Hair Cells

Sound transduction depends upon mechanosensitive channels localized on the hair-like bundles that project from the apical surface of cochlear hair cells. Hair bundles show a stair-case structure composed of rows of stereocilia, and each stereocilium contains a core of tightly-packed and uniformly-po...

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Detalles Bibliográficos
Autores principales: Olt, Jennifer, Mburu, Philomena, Johnson, Stuart L., Parker, Andy, Kuhn, Stephanie, Bowl, Mike, Marcotti, Walter, Brown, Steve D. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903700/
https://www.ncbi.nlm.nih.gov/pubmed/24475274
http://dx.doi.org/10.1371/journal.pone.0087331