Mitotic perturbations induced by Nek2 overexpression require interaction with TRF1 in breast cancer cells

NIMA-related kinase 2 (Nek2), a serine–threonine protein kinase, plays a major role in mitotic progression, including timing of mitotic entry, chromatin condensation, spindle organization, and cytokinesis. Nek2 overexpression results in premature centrosome separation, while kinase death Nek2 mutant...

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Detalles Bibliográficos
Autores principales: Lee, Jaehyung, Gollahon, Lauren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903712/
https://www.ncbi.nlm.nih.gov/pubmed/24091727
http://dx.doi.org/10.4161/cc.26589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903712/
https://www.ncbi.nlm.nih.gov/pubmed/24091727
http://dx.doi.org/10.4161/cc.26589

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