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Mitotic perturbations induced by Nek2 overexpression require interaction with TRF1 in breast cancer cells
NIMA-related kinase 2 (Nek2), a serine–threonine protein kinase, plays a major role in mitotic progression, including timing of mitotic entry, chromatin condensation, spindle organization, and cytokinesis. Nek2 overexpression results in premature centrosome separation, while kinase death Nek2 mutant...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903712/ https://www.ncbi.nlm.nih.gov/pubmed/24091727 http://dx.doi.org/10.4161/cc.26589 |