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Spinal Noradrenergic Modulation and the Role of the Alpha-2 Receptor in the Antinociceptive Effect of Intrathecal Nefopam in the Formalin Test

BACKGROUND: Nefopam has shown an analgesic effect on acute pain including postoperative pain. The reuptake of monoamines including serotonin and noradrenaline has been proposed as the mechanism of the analgesic action of nefopam, but it remains unclear. Although alpha-adrenergic agents are being wid...

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Detalles Bibliográficos
Autores principales: Jeong, Shin Ho, Heo, Bong Ha, Park, Sun Hong, Kim, Woong Mo, Lee, Hyung Gon, Yoon, Myung Ha, Choi, Jeong Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pain Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903796/
https://www.ncbi.nlm.nih.gov/pubmed/24478897
http://dx.doi.org/10.3344/kjp.2014.27.1.23