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17DD yellow fever vaccine: A double blind, randomized clinical trial of immunogenicity and safety on a dose-response study

Objective: To verify if the Bio-Manguinhos 17DD yellow fever vaccine (17DD-YFV) used in lower doses is as immunogenic and safe as the current formulation. Results: Doses from 27,476 IU to 587 IU induced similar seroconversion rates and neutralizing antibodies geometric mean titers (GMTs). Immunity o...

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Detalles Bibliográficos
Autores principales: Martins, Reinaldo M., Maia, Maria de Lourdes S., Farias, Roberto Henrique G., Camacho, Luiz Antonio B., Freire, Marcos S., Galler, Ricardo, Yamamura, Anna Maya Yoshida, Almeida, Luiz Fernando C., Lima, Sheila Maria B., Nogueira, Rita Maria R., Sá, Gloria Regina S., Hokama, Darcy A., de Carvalho, Ricardo, Freire, Ricardo Aguiar V., Filho, Edson Pereira, Leal, Maria da Luz Fernandes, Homma, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903908/
https://www.ncbi.nlm.nih.gov/pubmed/23364472
http://dx.doi.org/10.4161/hv.22982