GS-9219/VDC-1101 - a prodrug of the acyclic nucleotide PMEG has antitumor activity inspontaneous canine multiple myeloma

BACKGROUND: Multiple myeloma (MM) is an important human and canine cancer for which novel therapies remain necessary. VDC-1101 (formerly GS-9219), a novel double prodrug of the anti-proliferative nucleotide analog 9-(2-phosphonylmethoxyethyl) guanine (PMEG), possesses potent cytotoxic activity in vi...

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Detalles Bibliográficos
Autores principales: Thamm, Douglas H, Vail, David M, Kurzman, Ilene D, Babusis, Darius, Ray, Adrian S, Sousa-Powers, Noel, Tumas, Daniel B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904015/
https://www.ncbi.nlm.nih.gov/pubmed/24460928
http://dx.doi.org/10.1186/1746-6148-10-30

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904015/
https://www.ncbi.nlm.nih.gov/pubmed/24460928
http://dx.doi.org/10.1186/1746-6148-10-30

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