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Novel mechanism regulating endothelial permeability via T-cadherin-dependent VE-cadherin phosphorylation and clathrin-mediated endocytosis

T-cadherin is a unique member of the cadherin superfamily of adhesion molecules. In contrast to “classical” cadherins, T-cadherin lacks transmembrane and cytoplasmic domains and is anchored to the cell membrane via a glycosilphosphoinositol moiety. T-cadherin is predominantly expressed in cardiovasc...

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Detalles Bibliográficos
Autores principales: Semina, Ekaterina V., Rubina, Kseniya A., Sysoeva, Veronika Yu., Rutkevich, Pavel N., Kashirina, Natalia M., Tkachuk, Vsevolod A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904039/
https://www.ncbi.nlm.nih.gov/pubmed/24136461
http://dx.doi.org/10.1007/s11010-013-1867-4