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Polymorphisms within the Telomerase Reverse Transcriptase gene (TERT) in four breeds of dogs selected for difference in lifespan and cancer susceptibility

BACKGROUND: Enzymatic activity of Telomerase Reverse Transcriptase (TERT) is important in maintaining the telomere length and has been implicated in cancer and aging related pathology. Since cancer susceptibility as well as longevity of dogs vary between breeds, this study involved sequencing the en...

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Detalles Bibliográficos
Autores principales: McAloney, Camille A, Silverstein, Kevin A T, Modiano, Jaime F, Bagchi, Anindya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904191/
https://www.ncbi.nlm.nih.gov/pubmed/24423165
http://dx.doi.org/10.1186/1746-6148-10-20