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Prion protein and susceptibility to kainate-induced seizures: Genetic pitfalls in the use of PrP knockout mice
Prion protein (PrP) is a cell surface glycoprotein which is required for susceptibility to prion infection and disease. However, PrP is expressed in many different cell types located in numerous organs. Therefore, in addition to its role in prion diseases, PrP may have a large variety of other biolo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904312/ https://www.ncbi.nlm.nih.gov/pubmed/23851597 http://dx.doi.org/10.4161/pri.25738 |