HLA mismatches and hematopoietic cell transplantation: structural simulations assess the impact of changes in peptide binding specificity on transplant outcome

The success of hematopoietic cell transplantation from an unrelated donor depends in part on the degree of Human Histocompatibility Leukocyte Antigen (HLA) matching between donor and patient. We present a structure-based analysis of HLA mismatching, focusing on individual amino acid mismatches and t...

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Detalles Bibliográficos
Autores principales: Yanover, Chen, Petersdorf, Effie W., Malkki, Mari, Gooley, Ted, Spellman, Stephen, Velardi, Andrea, Bardy, Peter, Madrigal, Alejandro, Bignon, Jean-Denis, Bradley, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904355/
https://www.ncbi.nlm.nih.gov/pubmed/24482668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904355/
https://www.ncbi.nlm.nih.gov/pubmed/24482668

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