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PcrG protects the two long helical oligomerization domains of PcrV, by an interaction mediated by the intramolecular coiled-coil region of PcrG

BACKGROUND: PcrV is a hydrophilic translocator of type three secretion system (TTSS) and a structural component of the functional translocon. C-terminal helix of PcrV is essential for its oligomerization at the needle tip. Conformational changes within PcrV regulate the effector translocation. PcrG...

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Detalles Bibliográficos
Autores principales: Basu, Abhishek, Das, Urmisha, Dey, Supratim, Datta, Saumen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904411/
https://www.ncbi.nlm.nih.gov/pubmed/24460624
http://dx.doi.org/10.1186/1472-6807-14-5