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Allosteric modulation of GABA(A) receptors by extracellular ATP

BACKGROUND: The γ-aminobutyric acid type A receptor (GABA(A)R) is the primary receptor mediating fast synaptic inhibition in the brain and plays a critical role in modulation of neuronal excitability and neural networks. Previous studies have demonstrated that ATP and its nucleotide analogs may regu...

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Detalles Bibliográficos
Autores principales: Liu, Jun, Wang, Yu Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904413/
https://www.ncbi.nlm.nih.gov/pubmed/24456563
http://dx.doi.org/10.1186/1756-6606-7-6