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Range modulation in proton therapy planning: a simple method for mitigating effects of increased relative biological effectiveness at the end-of-range of clinical proton beams

BACKGROUND: The increase in relative biological effectiveness (RBE) of proton beams at the distal edge of the spread out Bragg peak (SOBP) is a well-known phenomenon that is difficult to quantify accurately in vivo. For purposes of treatment planning, disallowing the distal SOBP to fall within vulne...

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Detalles Bibliográficos
Autores principales: Buchsbaum, Jeffrey C, McDonald, Mark W, Johnstone, Peter AS, Hoene, Ted, Mendonca, Marc, Cheng, Chee-Wei, Das, Indra J, McMullen, Kevin P, Wolanski, Mark R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904459/
https://www.ncbi.nlm.nih.gov/pubmed/24383792
http://dx.doi.org/10.1186/1748-717X-9-2