The effect of piperine on midazolam plasma concentration in healthy volunteers, a research on the CYP3A-involving metabolism

Some studies showed that piperine (the alkaloid of piper nigrum) can change the activities of microsomal enzymes. Midazolam concentration is applied as a probe to determine the CYP3A enzyme activity. This study was done to determine piperine pretreatment role on midazolam plasma concentration. Twent...

Descripción completa

Detalles Bibliográficos
Autores principales: Rezaee, Mohammad Mahdi, Kazemi, Sohrab, Kazemi, Mohammad Taghi, Gharooee, Saeed, Yazdani, Elham, Gharooee, Hoda, Shiran, Mohammad Reza, Moghadamnia, Ali Akbar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904487/
https://www.ncbi.nlm.nih.gov/pubmed/24398010
http://dx.doi.org/10.1186/2008-2231-22-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904487/
https://www.ncbi.nlm.nih.gov/pubmed/24398010
http://dx.doi.org/10.1186/2008-2231-22-8

Ejemplares similares