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The effect of piperine on midazolam plasma concentration in healthy volunteers, a research on the CYP3A-involving metabolism

Some studies showed that piperine (the alkaloid of piper nigrum) can change the activities of microsomal enzymes. Midazolam concentration is applied as a probe to determine the CYP3A enzyme activity. This study was done to determine piperine pretreatment role on midazolam plasma concentration. Twent...

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Detalles Bibliográficos
Autores principales:	Rezaee, Mohammad Mahdi, Kazemi, Sohrab, Kazemi, Mohammad Taghi, Gharooee, Saeed, Yazdani, Elham, Gharooee, Hoda, Shiran, Mohammad Reza, Moghadamnia, Ali Akbar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904487/ https://www.ncbi.nlm.nih.gov/pubmed/24398010 http://dx.doi.org/10.1186/2008-2231-22-8

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