mCSM: predicting the effects of mutations in proteins using graph-based signatures

Motivation: Mutations play fundamental roles in evolution by introducing diversity into genomes. Missense mutations in structural genes may become either selectively advantageous or disadvantageous to the organism by affecting protein stability and/or interfering with interactions between partners....

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Detalles Bibliográficos
Autores principales: Pires, Douglas E. V., Ascher, David B., Blundell, Tom L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904523/
https://www.ncbi.nlm.nih.gov/pubmed/24281696
http://dx.doi.org/10.1093/bioinformatics/btt691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904523/
https://www.ncbi.nlm.nih.gov/pubmed/24281696
http://dx.doi.org/10.1093/bioinformatics/btt691

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