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Revisiting amino acid substitution matrices for identifying distantly related proteins

Motivation: Although many amino acid substitution matrices have been developed, it has not been well understood which is the best for similarity searches, especially for remote homology detection. Therefore, we collected information related to existing matrices, condensed it and derived a novel matr...

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Detalles Bibliográficos
Autores principales: Yamada, Kazunori, Tomii, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904525/
https://www.ncbi.nlm.nih.gov/pubmed/24281694
http://dx.doi.org/10.1093/bioinformatics/btt694