Cargando…

Structural basis for action by diverse antidepressants on biogenic amine transporters

The biogenic amine transporters (BATs) regulate endogenous neurotransmitter concentrations and are targets for a broad range of therapeutic agents that include selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs) and tricyclic antidepressants (TCAs)(1...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Hui, Goehring, April, Wang, Kevin H, Penmatsa, Aravind, Ressler, Ryan, Gouaux, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904662/
https://www.ncbi.nlm.nih.gov/pubmed/24121440
http://dx.doi.org/10.1038/nature12648