Ligand and Structure-Based Classification Models for Prediction of P-Glycoprotein Inhibitors

[Image: see text] The ABC transporter P-glycoprotein (P-gp) actively transports a wide range of drugs and toxins out of cells, and is therefore related to multidrug resistance and the ADME profile of therapeutics. Thus, development of predictive in silico models for the identification of P-gp inhibi...

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Detalles Bibliográficos
Autores principales: Klepsch, Freya, Vasanthanathan, Poongavanam, Ecker, Gerhard F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904775/
https://www.ncbi.nlm.nih.gov/pubmed/24050383
http://dx.doi.org/10.1021/ci400289j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904775/
https://www.ncbi.nlm.nih.gov/pubmed/24050383
http://dx.doi.org/10.1021/ci400289j

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