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Ligand and Structure-Based Classification Models for Prediction of P-Glycoprotein Inhibitors
[Image: see text] The ABC transporter P-glycoprotein (P-gp) actively transports a wide range of drugs and toxins out of cells, and is therefore related to multidrug resistance and the ADME profile of therapeutics. Thus, development of predictive in silico models for the identification of P-gp inhibi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904775/ https://www.ncbi.nlm.nih.gov/pubmed/24050383 http://dx.doi.org/10.1021/ci400289j |