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TFPI1 Mediates Resistance to Doxorubicin in Breast Cancer Cells by Inducing a Hypoxic-Like Response

Thrombin and hypoxia are important players in breast cancer progression. Breast cancers often develop drug resistance, but mechanisms linking thrombin and hypoxia to drug resistance remain unresolved. Our studies using Doxorubicin (DOX) resistant MCF7 breast cancer cells reveals a mechanism linking...

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Detalles Bibliográficos
Autores principales: Davies, Gerald F., Berg, Arnie, Postnikoff, Spike D. L., Wilson, Heather L., Arnason, Terra G., Kusalik, Anthony, Harkness, Troy A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904823/
https://www.ncbi.nlm.nih.gov/pubmed/24489651
http://dx.doi.org/10.1371/journal.pone.0084611