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Keap1 Cysteine 288 as a Potential Target for Diallyl Trisulfide-Induced Nrf2 Activation

Diallyl sulfide, diallyl disulfide, and daillyl trisulfide (DATS) are major volatile components of garlic oil. In this study, we assessed their relative potency in inducing antioxidant enzyme expression. Among the three organosulfur compounds, DATS was found to be most potent in inducing heme oxygen...

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Detalles Bibliográficos
Autores principales: Kim, Sanghyun, Lee, Hee-Geum, Park, Sin-Aye, Kundu, Joydeb Kumar, Keum, Young-Sam, Cha, Young-Nam, Na, Hye-Kyung, Surh, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904845/
https://www.ncbi.nlm.nih.gov/pubmed/24489685
http://dx.doi.org/10.1371/journal.pone.0085984