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Ras Effector Mutant Expression Suggest a Negative Regulator Inhibits Lung Tumor Formation

Lung cancer is currently the most deadly malignancy in industrialized countries and accounts for 18% of all cancer-related deaths worldwide. Over 70% of patients with non-small cell lung cancer (NSCLC) are diagnosed at a late stage, with a 5-year survival below 10%. KRAS and the EGFR are frequently...

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Detalles Bibliográficos
Autores principales: Vandal, Guillaume, Geiling, Benjamin, Dankort, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904846/
https://www.ncbi.nlm.nih.gov/pubmed/24489653
http://dx.doi.org/10.1371/journal.pone.0084745