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Ras Effector Mutant Expression Suggest a Negative Regulator Inhibits Lung Tumor Formation
Lung cancer is currently the most deadly malignancy in industrialized countries and accounts for 18% of all cancer-related deaths worldwide. Over 70% of patients with non-small cell lung cancer (NSCLC) are diagnosed at a late stage, with a 5-year survival below 10%. KRAS and the EGFR are frequently...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904846/ https://www.ncbi.nlm.nih.gov/pubmed/24489653 http://dx.doi.org/10.1371/journal.pone.0084745 |