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A1M/α(1)-Microglobulin Protects from Heme-Induced Placental and Renal Damage in a Pregnant Sheep Model of Preeclampsia

Preeclampsia (PE) is a serious pregnancy complication that manifests as hypertension and proteinuria after the 20(th) gestation week. Previously, fetal hemoglobin (HbF) has been identified as a plausible causative factor. Cell-free Hb and its degradation products are known to cause oxidative stress...

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Detalles Bibliográficos
Autores principales: Wester-Rosenlöf, Lena, Casslén, Vera, Axelsson, Josefin, Edström-Hägerwall, Anneli, Gram, Magnus, Holmqvist, Madlene, Johansson, Martin E., Larsson, Iréne, Ley, David, Marsal, Karel, Mörgelin, Matthias, Rippe, Bengt, Rutardottir, Sigurbjörg, Shohani, Behnaz, Åkerström, Bo, Hansson, Stefan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904882/
https://www.ncbi.nlm.nih.gov/pubmed/24489717
http://dx.doi.org/10.1371/journal.pone.0086353