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A1M/α(1)-Microglobulin Protects from Heme-Induced Placental and Renal Damage in a Pregnant Sheep Model of Preeclampsia
Preeclampsia (PE) is a serious pregnancy complication that manifests as hypertension and proteinuria after the 20(th) gestation week. Previously, fetal hemoglobin (HbF) has been identified as a plausible causative factor. Cell-free Hb and its degradation products are known to cause oxidative stress...
Autores principales: | Wester-Rosenlöf, Lena, Casslén, Vera, Axelsson, Josefin, Edström-Hägerwall, Anneli, Gram, Magnus, Holmqvist, Madlene, Johansson, Martin E., Larsson, Iréne, Ley, David, Marsal, Karel, Mörgelin, Matthias, Rippe, Bengt, Rutardottir, Sigurbjörg, Shohani, Behnaz, Åkerström, Bo, Hansson, Stefan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904882/ https://www.ncbi.nlm.nih.gov/pubmed/24489717 http://dx.doi.org/10.1371/journal.pone.0086353 |
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