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Small Activating RNA Restores the Activity of the Tumor Suppressor HIC-1 on Breast Cancer

HIC-1 is a gene that is hypermethylated in cancer, and commonly downregulated in human breast cancer. However, the precise mechanisms and molecular pathways regulated by HIC-1 remain unclear. We assessed HIC-1 expression on a tissue microarray containing 80 cases of breast cancer. We also analyzed i...

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Detalles Bibliográficos
Autores principales: Zhao, Feng, Pan, Shengli, Gu, Yan, Guo, Shanyu, Dai, Qiancheng, Yu, Yingyan, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904905/
https://www.ncbi.nlm.nih.gov/pubmed/24489730
http://dx.doi.org/10.1371/journal.pone.0086486