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Network Oscillations Drive Correlated Spiking of ON and OFF Ganglion Cells in the rd1 Mouse Model of Retinal Degeneration

Following photoreceptor degeneration, ON and OFF retinal ganglion cells (RGCs) in the rd-1/rd-1 mouse receive rhythmic synaptic input that elicits bursts of action potentials at ∼10 Hz. To characterize the properties of this activity, RGCs were targeted for paired recording and morphological classif...

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Detalles Bibliográficos
Autores principales: Margolis, David J., Gartland, Andrew J., Singer, Joshua H., Detwiler, Peter B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904909/
https://www.ncbi.nlm.nih.gov/pubmed/24489706
http://dx.doi.org/10.1371/journal.pone.0086253