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Interferon-γ Induces Expression of MHC Class II on Intestinal Epithelial Cells and Protects Mice from Colitis

Immune responses against intestinal microbiota contribute to the pathogenesis of inflammatory bowel diseases (IBD) and involve CD4(+) T cells, which are activated by major histocompatibility complex class II (MHCII) molecules on antigen-presenting cells (APCs). However, it is largely unexplored how...

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Detalles Bibliográficos
Autores principales: Thelemann, Christoph, Eren, Remzi Onur, Coutaz, Manuel, Brasseit, Jennifer, Bouzourene, Hanifa, Rosa, Muriel, Duval, Anais, Lavanchy, Christine, Mack, Vanessa, Mueller, Christoph, Reith, Walter, Acha-Orbea, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904943/
https://www.ncbi.nlm.nih.gov/pubmed/24489792
http://dx.doi.org/10.1371/journal.pone.0086844