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Genetic Variants in PCSK1 Gene Are Associated with the Risk of Coronary Artery Disease in Type 2 Diabetes in a Chinese Han Population: A Case Control Study

BACKGROUND: Insulin and glucagon-like peptide 1 (GLP-1), converted by proprotein convertase 1 (PC1/3) from proinsulin and proglucagon, are associated with type 2 diabetes (T2DM) and coronary artery disease (CAD). The aim of this study is to investigate the association of PCSK1 gene, which encodes PC...

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Detalles Bibliográficos
Autores principales: Wei, Xiaowei, Ma, Xiaowei, Lu, Ran, Bai, Ge, Zhang, Jianwei, Deng, Ruifen, Gu, Nan, Feng, Nan, Guo, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904973/
https://www.ncbi.nlm.nih.gov/pubmed/24489861
http://dx.doi.org/10.1371/journal.pone.0087168