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Association between the PARP1 Val762Ala Polymorphism and Cancer Risk: Evidence from 43 Studies

BACKGROUND: Poly (ADP-ribose) polymerase-1 (PARP-1) plays critical roles in the detection and repair of damaged DNA, as well as cell proliferation and death. Numerous studies have examined the associations between PARP1 Val762Ala (rs1136410 T>C) polymorphism and cancer susceptibility; nevertheles...

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Detalles Bibliográficos
Autores principales: Hua, Rui-Xi, Li, He-Ping, Liang, Yan-Bing, Zhu, Jin-Hong, Zhang, Bing, Ye, Sheng, Dai, Qiang-Sheng, Xiong, Shi-Qiu, Gu, Yong, Sun, Xiang-Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904982/
https://www.ncbi.nlm.nih.gov/pubmed/24489833
http://dx.doi.org/10.1371/journal.pone.0087057