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Association between the PARP1 Val762Ala Polymorphism and Cancer Risk: Evidence from 43 Studies
BACKGROUND: Poly (ADP-ribose) polymerase-1 (PARP-1) plays critical roles in the detection and repair of damaged DNA, as well as cell proliferation and death. Numerous studies have examined the associations between PARP1 Val762Ala (rs1136410 T>C) polymorphism and cancer susceptibility; nevertheles...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904982/ https://www.ncbi.nlm.nih.gov/pubmed/24489833 http://dx.doi.org/10.1371/journal.pone.0087057 |