Cargando…

On the Characterization of Intermediates in the Isodesmic Aggregation Pathway of Hen Lysozyme at Alkaline pH

Protein aggregation leading to formation of amyloid fibrils is a symptom of several diseases like Alzheimer’s, type 2 diabetes and so on. Elucidating the poorly understood mechanism of such phenomena entails the difficult task of characterizing the species involved at each of the multiple steps in t...

Descripción completa

Detalles Bibliográficos
Autores principales: Ravi, Vijay Kumar, Swain, Tulsi, Chandra, Nividh, Swaminathan, Rajaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904990/
https://www.ncbi.nlm.nih.gov/pubmed/24489883
http://dx.doi.org/10.1371/journal.pone.0087256