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Inhibition of the K(+) Channel K(Ca)3.1 Reduces TGF-β1-Induced Premature Senescence, Myofibroblast Phenotype Transition and Proliferation of Mesangial Cells

OBJECTIVE: K(Ca)3.1 channel participates in many important cellular functions. This study planned to investigate the potential involvement of K(Ca)3.1 channel in premature senescence, myofibroblast phenotype transition and proliferation of mesangial cells. METHODS & MATERIALS: Rat mesangial cell...

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Detalles Bibliográficos
Autores principales: Fu, Rong-Guo, Zhang, Tao, Wang, Li, Du, Yan, Jia, Li-Ning, Hou, Jing-Jing, Yao, Gang-Lian, Liu, Xiao-Dan, Zhang, Lei, Chen, Ling, Gui, Bao-Song, Xue, Rong-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905019/
https://www.ncbi.nlm.nih.gov/pubmed/24489911
http://dx.doi.org/10.1371/journal.pone.0087410