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Productively Infected Murine Kaposi's Sarcoma-Like Tumors Define New Animal Models for Studying and Targeting KSHV Oncogenesis and Replication

Kaposi's sarcoma (KS) is an AIDS-defining cancer caused by the KS-associated herpesvirus (KSHV). KS tumors are composed of KSHV-infected spindle cells of vascular origin with aberrant neovascularization and erythrocyte extravasation. KSHV genes expressed during both latent and lytic replicative...

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Detalles Bibliográficos
Autores principales: Ashlock, Brittany M., Ma, Qi, Issac, Biju, Mesri, Enrique A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905023/
https://www.ncbi.nlm.nih.gov/pubmed/24489895
http://dx.doi.org/10.1371/journal.pone.0087324