Cargando…
Productively Infected Murine Kaposi's Sarcoma-Like Tumors Define New Animal Models for Studying and Targeting KSHV Oncogenesis and Replication
Kaposi's sarcoma (KS) is an AIDS-defining cancer caused by the KS-associated herpesvirus (KSHV). KS tumors are composed of KSHV-infected spindle cells of vascular origin with aberrant neovascularization and erythrocyte extravasation. KSHV genes expressed during both latent and lytic replicative...
Autores principales: | Ashlock, Brittany M., Ma, Qi, Issac, Biju, Mesri, Enrique A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905023/ https://www.ncbi.nlm.nih.gov/pubmed/24489895 http://dx.doi.org/10.1371/journal.pone.0087324 |
Ejemplares similares
-
Molecular and Cellular Mechanisms of KSHV Oncogenesis of Kaposi's Sarcoma Associated with HIV/AIDS
por: Cavallin, Lucas E., et al.
Publicado: (2014) -
PDGFRA defines the mesenchymal stem cell Kaposi’s sarcoma progenitors by enabling KSHV oncogenesis in an angiogenic environment
por: Naipauer, Julian, et al.
Publicado: (2019) -
KSHV-mediated ROS induction defines novel therapeutic targets in Kaposi’s sarcoma
por: Cavallin, Lucas E, et al.
Publicado: (2010) -
Kaposi’s sarcoma herpesvirus activates the hypoxia response to usurp HIF2α-dependent translation initiation for replication and oncogenesis
por: Méndez-Solís, Omayra, et al.
Publicado: (2021) -
Review of the distribution of Kaposi's sarcoma-associated herpesvirus (KSHV) in Africa in relation to the incidence of Kaposi's sarcoma
por: Dedicoat, M, et al.
Publicado: (2003)