New Mechanisms to Explain the Effects of Added Lactose Fines on the Dispersion Performance of Adhesive Mixtures for Inhalation

Fine excipient particles or ‘fines’ have been shown to improve the dispersion performance of carrier-based formulations for dry powder inhalation. Mechanistic formulation studies have focussed mainly on explaining this positive effect. Previous studies have shown that higher drug contents may cause...

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Detalles Bibliográficos
Autores principales: Grasmeijer, Floris, Lexmond, Anne J., van den Noort, Maarten, Hagedoorn, Paul, Hickey, Anthony J., Frijlink, Henderik W., de Boer, Anne H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905031/
https://www.ncbi.nlm.nih.gov/pubmed/24489969
http://dx.doi.org/10.1371/journal.pone.0087825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905031/
https://www.ncbi.nlm.nih.gov/pubmed/24489969
http://dx.doi.org/10.1371/journal.pone.0087825

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