Cargando…

The proteolytic YB-1 fragment interacts with DNA repair machinery and enhances survival during DNA damaging stress

The Y-box binding protein 1 (YB-1) is a DNA/RNA-binding nucleocytoplasmic shuttling protein whose regulatory effect on many DNA and RNA-dependent events is determined by its localization in the cell. We have shown previously that YB-1 is cleaved by 20S proteasome between E219 and G220, and the trunc...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Ekaterina R, Selyutina, Anastasia A, Buldakov, Ilya A, Evdokimova, Valentina, Ovchinnikov, Lev P, Sorokin, Alexey V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905071/
https://www.ncbi.nlm.nih.gov/pubmed/24107631
http://dx.doi.org/10.4161/cc.26670