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The proteolytic YB-1 fragment interacts with DNA repair machinery and enhances survival during DNA damaging stress
The Y-box binding protein 1 (YB-1) is a DNA/RNA-binding nucleocytoplasmic shuttling protein whose regulatory effect on many DNA and RNA-dependent events is determined by its localization in the cell. We have shown previously that YB-1 is cleaved by 20S proteasome between E219 and G220, and the trunc...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905071/ https://www.ncbi.nlm.nih.gov/pubmed/24107631 http://dx.doi.org/10.4161/cc.26670 |